Mucosal Immunology and Vaccine Development

Vaccines Against Infectious Diseases and Cancers

Vaccines against infectious diseases represent a therapeutic vaccine against chronic infectious diseases aim at eliciting broad humoral and cellular immune responses against multiple target antigens. The development of these vaccines will help to establish substitute markers of protection in humans and thus will boost the subsequent development of capable prophylactic vaccines. A grouping of synthetic small-molecule drugs andimmunotherapeutics is likely to represent a powerful means of controlling chronic infections in the future. There are a number of scientific challenges which require multidisciplinary teams to solve problems in developing new immunogens. This has challenged our existing knowledge about protein structure and conformation, microbial pathogenicity and the immune system. Cancer cells are generally ignored by the immune system. This is because for the most of the part are more closely resemble cells that belong in the body than pathogens, such as bacterial cells or viruses. The goal of cancer vaccines is to provoke the immune system to identify cancercells as foreign and attack them.